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Schuh lab - meiosis in mammalian oocytes

To become a fertilizable egg, an oocyte has to eliminate half of the chromosomes into a small polar body, because the other half will be contributed by the sperm during fertilization. It is very important that we better understand this process, because errors during chromosome elimination result in aneuploid embryos and thus miscarriages, genetic disorders, or infertility.

This site is created by a research group led by Melina Schuh at the MRC Laboratory of Molecular Biology.

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